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Oocyte Cryopreservation Program and Success Rates
Fertility preservation through oocyte (egg) freezing allows women to store eggs at a younger age for use when they are older and is now a viable option for family planning. Whether eggs are being cryopreserved as a medical emergency in the setting of a newly-diagnosed cancer or for personal reasons, the technology holds great promise for women of reproductive age. To date, there are over 2000 births worldwide (greater than 1000 reported in the last five years) as a result of egg freezing.
The process involves stimulating eggs in the woman's ovaries and then harvesting and storing those eggs for use at a later date. Oocyte quality is best when a woman is in her reproductive prime (age 16 to 28). Many eggs are usually still of good quality in the mid-reproductive years (age 29 to 38) and may remain usable (but with diminished chance for producing pregnancy) in the late-reproductive period (age 39 to 44). If necessary or desired, it is best to have eggs that are frozen when they are of the best quality possible. For instance, eggs frozen at the age of 35 are more usable than fresh oocytes produced at 43 years of age.
The center has a staff dedicated to the egg freezing program to assure patients are properly cared for, counseled and supported. We know this is a big decision for many women and we want to make the process as comfortable and easy as possible. To date, more than 1000 women have chosen to freeze their eggs with us; 80% were for the purpose of deferred reproduction and 20% for medical indications.
Our Success Rates
We have achieved significant success with egg freezing and thawing. As of the beginning of this year, more than 80 cycles (medical, elective and donor egg) have been performed where both freezing and thawing have been completed. 26 women have delivered 33 liveborn children (7 sets of twins), four women have healthy ongoing pregnancies and six women have miscarried. Eggs in these cycles were obtained from women up to age 42 years with overall success similar to what we see in our general IVF patients matched for age.
All pregnancies to date have occurred as a result of eggs frozen up to age 42, although only four thaw cycles have been performed with eggs cryopreserved at age 43 or above. We feel confident as our egg freezing program expands and more women are ready to thaw and use their stored oocytes, the success rates will remain similar to those of our regular, fresh IVF cycles by age.
If you are interested in or need more preliminary information about egg freezing, learn more about how to get started with egg freezing.
(Note: A comparison of clinic success rates may not be meaningful because patient medical characteristics, treatment approaches and entrance criteria for ART may vary from clinic to clinic.)
Cryopreservation with Donor Eggs
Egg freezing is also available to help simplify the process of using donor eggs by eliminating the need to synchronize the recipient’s cycle with the donor’s cycle. To date, 20 of the cycles performed where both freezing and thawing have been completed used donated eggs. 12 women have delivered 16 liveborn children (four sets of twins) and there are two healthy ongoing pregnancies. This translates to a 60% success rate.
Patient Orientation Sessions
Any patient undergoing an Egg Freezing (EF) cycle must attend an onsite orientation session conducted by our nursing staff before beginning treatment. If applicable, partners are encouraged to attend this session as well. To provide additional review of the information, the orientation presentation is now available for you to review online. Please note, this availability does not eliminate the need to attend an onsite session. View the presentation.