Recent Publications by Dr. David Keefe
Publications
| 1. | Johnson, Joshua; Keefe, David L.. "Ovarian Aging: Breaking Up Is Hard to Fix". Science translational medicine. 2013; 5: (#241002) |
| 2. | Liu, Mengyuan; Yin, Yu; Ye, Xiaoying; Zeng, Ming; Zhao, Qiang; Keefe, David L; Liu, Lin. "Resveratrol protects against age-associated infertility in mice". Human reproduction. 2013; 28: 707 (#249062) |
| 3. | Liu, Jinmiao; Liu, Mengyuan; Ye, Xiaoying; Liu, Kai; Huang, Junjiu; Wang, Lingling; Ji, Guangzhen; Liu, Na; Tang, Xiangdong; Baltz, Jay M; Keefe, David L; Liu, Lin. "Delay in oocyte aging in mice by the antioxidant N-acetyl-L-cysteine (NAC)". Human reproduction. 2012; 27: 1411 (#166884) |
| 4. | Wang, Fang; Yin, Yu; Ye, Xiaoying; Liu, Kai; Zhu, Haiying; Wang, Lingling; Chiourea, Maria; Okuka, Maja; Ji, Guangzhen; Dan, Jiameng; Zuo, Bingfeng; Li, Minshu; Zhang, Qian; Liu, Na; Chen, Lingyi; Pan, Xinghua; Gagos, Sarantis; Keefe, David L; Liu, Lin. "Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells". Cell research. 2012; 22: 757 (#166038) |
| 5. | Huang, Junjiu; Wang, Fang; Okuka, Maja; Liu, Na; Ji, Guangzhen; Ye, Xiaoying; Zuo, Bingfeng; Li, Minshu; Liang, Ping; Ge, William W; Tsibris, John Cm; Keefe, David L; Liu, Lin. "Association of telomere length with authentic pluripotency of ES/iPS cells". Cell research. 2011; 21: 779 (#133642) |
| 6. | Liu, Zhong; Hu, Zhe; Pan, Xinghua; Li, Minshu; Togun, Taiwo A; Tuck, David; Pelizzola, Mattia; Huang, Junjiu; Ye, Xiaoying; Yin, Yu; Liu, Mengyuan; Li, Chao; Chen, Zhisheng; Wang, Fang; Zhou, Lingjun; Chen, Lingyi; Keefe, David L; Liu, Lin. "Germline competency of parthenogenetic embryonic stem cells from immature oocytes of adult mouse ovary". Human molecular genetics. 2011; 20: 1339 (#133643) |
| 7. | Agarwal, Suneet; Loh, Yuin-Han; McLoughlin, Erin M; Huang, Junjiu; Park, In-Hyun; Miller, Justine D; Huo, Hongguang; Okuka, Maja; Dos Reis, Rosana Maria; Loewer, Sabine; Ng, Huck-Hui; Keefe, David L; Goldman, Frederick D; Klingelhutz, Aloysius J; Liu, Lin; Daley, George Q. "Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients". Nature. 2010; 464: 292 (#133647) |
| 8. | Huang, Junjiu; Okuka, Maja; McLean, Mark; Keefe, David L; Liu, Lin. "Telomere susceptibility to cigarette smoke-induced oxidative damage and chromosomal instability of mouse embryos in vitro". Free radical biology & medicine. 2010; 48: 1663 (#133645) |
| 9. | Huang, Junjiu; Okuka, Maja; Wang, Fang; Zuo, Bingfeng; Liang, Ping; Kalmbach, Keri; Liu, Lin; Keefe, David L. "Generation of pluripotent stem cells from eggs of aging mice". Aging Cell. 2010; 9: 113 (#133646) |
| 10. | Liu, Na; Enkemann, Steven A; Liang, Ping; Hersmus, Remko; Zanazzi, Claudia; Huang, Junjiu; Wu, Chao; Chen, Zhisheng; Looijenga, Leendert H J; Keefe, David L; Liu, Lin. "Genome-wide gene expression profiling reveals aberrant MAPK and Wnt signaling pathways associated with early parthenogenesis". Journal of molecular cell biology. 2010; 2: 333 (#133644) |
| 11. | Palatini, P; Jung, W; Shlyakhto, E; Botha, J; Bush, C; Keefe, D L. "Maintenance of blood-pressure-lowering effect following a missed dose of aliskiren, irbesartan or ramipril: results of a randomized, double-blind study". Journal of human hypertension. 2010; 24: 93 (#101969) |
| 12. | Quinn, Gwendolyn P; Vadaparampil, Susan T; Jacobsen, Paul B; Knapp, Caprice; Keefe, David L; Bell, Geri E. "Frozen hope: fertility preservation for women with cancer". Journal of Midwifery & Women's Health. 2010; 55: 175 (#144118) |
| 13. | Chen, Zhisheng; Liu, Zhong; Huang, Junjiu; Amano, Tomokazu; Li, Chao; Cao, Shanbo; Wu, Chao; Liu, Bodu; Zhou, Lingjun; Carter, Mark G; Keefe, David L; Yang, Xiangzhong; Liu, Lin. "Birth of Parthenote Mice Directly from Parthenogenetic Embryonic Stem Cells". Stem cells. 2009; 27: 2136 (#101968) |
| 14. | Huang, Junjiu; Okuka, Maja; McLean, Mark; Keefe, David L; Liu, Lin. "Effects of cigarette smoke on fertilization and embryo development in vivo". Fertility & sterility. 2009; 92: 1456 (#101972) |
| 15. | Keefe, David L; Liu, Lin. "Telomeres and reproductive aging". Reproduction, fertility & development. 2009; 21: 10 (#101971) |
| 16. | Li, Chao; Chen, Zhisheng; Liu, Zhong; Huang, Junjiu; Zhang, Wei; Zhou, Lingjun; Keefe, David L; Liu, Lin. "Correlation of expression and methylation of imprinted genes with pluripotency of parthenogenetic embryonic stem cells". Human molecular genetics. 2009; 18: 2177 (#101970) |
| 17. | Quinn, Gwendolyn P; Vadaparampil, Susan T; Lee, Ji-Hyun; Jacobsen, Paul B; Bepler, Gerold; Lancaster, Johnathan; Keefe, David L; Albrecht, Terrance L. "Physician referral for fertility preservation in oncology patients: a national study of practice behaviors". Journal of clinical oncology. 2009; 27: 5952 (#144119) |
| 18. | Silberstein, Tali; Saphier, Oshra; Paz-Tal, Ofra; Gonzalez, Liliana; Keefe, David L; Trimarchi, James R. "Trace element concentrations in follicular fluid of small follicles differ from those in blood serum, and may represent long-term exposure". Fertility & sterility. 2009; 91: 1771 (#101974) |
| 19. | Huang, Junjiu; Deng, Kai; Wu, Haojia; Liu, Zhong; Chen, Zhisheng; Cao, Shanbo; Zhou, Lingjun; Ye, Xiaoying; Keefe, David L; Liu, Lin. "Efficient production of mice from embryonic stem cells injected into four- or eight-cell embryos by piezo micromanipulation". Stem cells. 2008; 26: 1883 (#101973) |
| 20. | Liu, Lin; Keefe, David L. "Defective cohesin is associated with age-dependent misaligned chromosomes in oocytes". Reproductive biomedicine online. 2008; 16: 103 (#101975) |
| 21. | Keefe, D L. "Telomeres and meiosis in health and disease". Cellular & molecular life sciences: CMLS. 2007; 64: 115 (#101979) |
| 22. | Keefe, D L; Liu, L; Marquard, K. "Telomeres and aging-related meiotic dysfunction in women". Cellular & molecular life sciences: CMLS. 2007; 64: 139 (#101980) |
| 23. | Liu, Lin; Bailey, Susan M; Okuka, Maja; Munoz, Purificacion; Li, Chao; Zhou, Lingjun; Wu, Chao; Czerwiec, Eva; Sandler, Laurel; Seyfang, Andreas; Blasco, Maria A; Keefe, David L. "Telomere lengthening early in development". Nature cell biology. 2007; 9: 1436 (#101976) |
| 24. | Liu, Lin; Keefe, David L. "Nuclear transfer methods to study aging". Methods in molecular biology. 2007; 371: 191 (#101977) |
| 25. | Liu, Yifei; Wu, Chao; Lyu, Qifeng; Yang, Dongzi; Albertini, David F; Keefe, David L; Liu, Lin. "Germline stem cells and neo-oogenesis in the adult human ovary". Developmental biology (Orlando). 2007; 306: 112 (#101978) |
| 26. | Dai, Yunping; Wang, Lili; Wang, Haiping; Liu, Ying; Li, Ning; Lyu, Qifeng; Keefe, David L; Albertini, David F; Liu, Lin. "Fate of centrosomes following somatic cell nuclear transfer (SCNT) in bovine oocytes". Reproduction. 2006; 131: 1051 (#101983) |
| 27. | Keefe, David L; Marquard, Kerri; Liu, Lin. "The telomere theory of reproductive senescence in women". Current opinion in obstetrics & gynecology. 2006; 18: 280 (#101982) |
| 28. | Navarro, Paula A A S; Liu, Lin; Ferriani, Rui A; Keefe, David L. "Arsenite induces aberrations in meiosis that can be prevented by coadministration of N-acetylcysteine in mice". Fertility & sterility. 2006; 85 Suppl 1: 1187 (#101984) |
| 29. | Silberstein, T; MacLaughlin, D T; Shai, I; Trimarchi, J R; Lambert-Messerlian, G; Seifer, D B; Keefe, D L; Blazar, A S. "Mullerian inhibiting substance levels at the time of HCG administration in IVF cycles predict both ovarian reserve and embryo morphology". Human reproduction. 2006; 21: 159 (#101988) |
| 30. | Silberstein, Tali; Saphier, Oshra; Paz-Tal, Ofra; Trimarchi, James R; Gonzalez, Liliana; Keefe, David L. "Lead concentrates in ovarian follicle compromises pregnancy". Journal of trace elements in medicine & biology. 2006; 20: 205 (#101981) |
| 31. | Trimarchi, James Robert; Keefe, David L. "Assessing the quality of oocytes derived from in vitro maturation: are we looking under the lamppost?". Fertility & sterility. 2006; 85: 839 (#101985) |
| 32. | Keefe, David L; Franco, Sonia; Liu, Lin; Trimarchi, James; Cao, Benning; Weitzen, Sherry; Agarwal, Shoba; Blasco, Maria A. "Telomere length predicts embryo fragmentation after in vitro fertilization in women--toward a telomere theory of reproductive aging in women". American journal of obstetrics & gynecology. 2005; 192: 1256 (#101989) |
| 33. | Keefe, David L; Parry, John P. "New approaches to assisted reproductive technologies". Seminars in reproductive medicine. 2005; 23: 301 (#101986) |
| 34. | Navarro, Paula A A S; Liu, Lin; Trimarchi, James R; Ferriani, Rui A; Keefe, David L. "Noninvasive imaging of spindle dynamics during mammalian oocyte activation". Fertility & sterility. 2005; 83 Suppl 1: 1197 (#101990) |
| 35. | Silberstein, Tali; Trimarchi, James R; Gonzalez, Liliana; Keefe, David L; Blazar, Andrew S. "Pregnancy outcome in in vitro fertilization decreases to a plateau with repeated cycles". Fertility & sterility. 2005; 84: 1043 (#101987) |
| 36. | Stachenfeld, Nina S; Keefe, David L; Taylor, Hugh S. "Responses to a saline load in gonadotropin-releasing hormone antagonist-pretreated premenopausal women receiving progesterone or estradiol-progesterone therapy". Journal of clinical endocrinology & metabolism. 2005; 90: 386 (#101993) |
| 37. | Abizaid, Alfonso; Horvath, Balazs; Keefe, David L; Leranth, Csaba; Horvath, Tamas L. "Direct visual and circadian pathways target neuroendocrine cells in primates". European journal of neuroscience. 2004; 20: 2767 (#101991) |
| 38. | Blazar, Andrew S; Hogan, Joseph W; Frankfurter, David; Hackett, Richard; Keefe, David L. "Serum estradiol positively predicts outcomes in patients undergoing in vitro fertilization". Fertility & sterility. 2004; 81: 1707 (#101996) |
| 39. | Frankfurter, David; Trimarchi, James B; Silva, Celso P; Keefe, David L. "Middle to lower uterine segment embryo transfer improves implantation and pregnancy rates compared with fundal embryo transfer". Fertility & sterility. 2004; 81: 1273 (#101998) |
| 40. | Frankfurter, David; Trimarchi, James; Hackett, Rick; Meng, Li; Keefe, David. "Monozygotic pregnancies from transfers of zona-free blastocysts". Fertility & sterility. 2004; 82: 483 (#144321) |
| 41. | Liu, Lin; Czerwiec, Eva; Keefe, David L. "Effect of ploidy and parental genome composition on expression of Oct-4 protein in mouse embryos". Gene expression patterns. 2004; 4: 433 (#101997) |
| 42. | Liu, Lin; DiGirolamo, Carla M; Navarro, Paula A A S; Blasco, Maria A; Keefe, David L. "Telomerase deficiency impairs differentiation of mesenchymal stem cells". Experimental cell research. 2004; 294: 1 (#102001) |
| 43. | Liu, Lin; Franco, Sonia; Spyropoulos, Barbara; Moens, Peter B; Blasco, Maria A; Keefe, David L. "Irregular telomeres impair meiotic synapsis and recombination in mice". Proceedings of the National Academy of Sciences of the United States of America. 2004; 101: 6496 (#101999) |
| 44. | Liu, Lin; Keefe, David L. "Nuclear origin of aging-associated meiotic defects in senescence-accelerated mice". Biology of reproduction. 2004; 71: 1724 (#101994) |
| 45. | Navarro, Paula A A S; Liu, Lin; Keefe, David L. "In vivo effects of arsenite on meiosis, preimplantation development, and apoptosis in the mouse". Biology of reproduction. 2004; 70: 980 (#102002) |
| 46. | Pelletier, Cory; Keefe, David L; Trimarchi, James R. "Noninvasive polarized light microscopy quantitatively distinguishes the multilaminar structure of the zona pellucida of living human eggs and embryos". Fertility & sterility. 2004; 81 Suppl 1: 850 (#102000) |
| 47. | Silberstein, Tali; Weitzen, Sherry; Frankfurter, David; Trimarchi, James R; Keefe, David L; Plosker, Shayne M. "Cannulation of a resistant internal os with the malleable outer sheath of a coaxial soft embryo transfer catheter does not affect in vitro fertilization-embryo transfer outcome". Fertility & sterility. 2004; 82: 1402 (#101992) |
| 48. | Sun, Xiao-Fang; Wang, Wei-Hua; Keefe, David L. "Overheating is detrimental to meiotic spindles within in vitro matured human oocytes". Zygote. 2004; 12: 65 (#101995) |
| 49. | Dubowy, Rebecca L; Feinberg, Ronald F; Keefe, David L; Doncel, Gustavo F; Williams, Shaun C; McSweet, Juliette C; Kliman, Harvey J. "Improved endometrial assessment using cyclin E and p27". Fertility & sterility. 2003; 80: 146 (#102005) |
| 50. | Frankfurter, David; Silva, Celso P; Mota, Francisco; Trimarchi, James B; Keefe, David L. "The transfer point is a novel measure of embryo placement". Fertility & sterility. 2003; 79: 1416 (#102006) |
| 51. | Keefe, David; Liu, Lin; Wang, Wei; Silva, Celso. "Imaging meiotic spindles by polarization light microscopy: principles and applications to IVF". Reproductive biomedicine online. 2003; 7: 24 (#133648) |
| 52. | Liu, Lin; Trimarchi, James R; Navarro, Paula; Blasco, Maria A; Keefe, David L. "Oxidative stress contributes to arsenic-induced telomere attrition, chromosome instability, and apoptosis". Journal of biological chemistry. 2003; 278: 31998 (#102007) |
| 53. | Pepperell, John R; Porterfield, D Marshall; Keefe, David L; Behrman, Harold R; Smith, Peter J S. "Control of ascorbic acid efflux in rat luteal cells: role of intracellular calcium and oxygen radicals". American journal of physiology. Cell physiology. 2003; 285: C642 (#102008) |
| 54. | Stachenfeld, Nina S; Taylor, Hugh S; Leone, Cheryl A; Keefe, David L. "Oestrogen effects on urine concentrating response in young women". Journal of physiology. 2003; 552: 869 (#102003) |
| 55. | Keefe, David L. "Sex hormones and neural mechanisms". Archives of sexual behaviour. 2002; 31: 401 (#102012) |
| 56. | Liu, Lin; Blasco, Maria A; Keefe, David L. "Requirement of functional telomeres for metaphase chromosome alignments and integrity of meiotic spindles". EMBO reports. 2002; 3: 230 (#102017) |
| 57. | Liu, Lin; Blasco, Maria; Trimarchi, James; Keefe, David. "An essential role for functional telomeres in mouse germ cells during fertilization and early development". Developmental biology (Orlando). 2002; 249: 74 (#133649) |
| 58. | Liu, Lin; Keefe, David L. "Ageing-associated aberration in meiosis of oocytes from senescence-accelerated mice". Human reproduction. 2002; 17: 2678 (#102011) |
| 59. | Liu, Lin; Trimarchi, James R; Keefe, David L. "Haploidy but not parthenogenetic activation leads to increased incidence of apoptosis in mouse embryos". Biology of reproduction. 2002; 66: 204 (#102019) |
| 60. | Liu, Lin; Trimarchi, James R; Smith, Peter J S; Keefe, David L. "Checkpoint for DNA integrity at the first mitosis after oocyte activation". Molecular reproduction & development. 2002; 62: 277 (#102015) |
| 61. | Liu, Lin; Trimarchi, James R; Smith, Peter J S; Keefe, David L. "Mitochondrial dysfunction leads to telomere attrition and genomic instability". Aging Cell. 2002; 1: 40 (#102004) |
| 62. | Stachenfeld, Nina S; Keefe, David L. "Estrogen effects on osmotic regulation of AVP and fluid balance". American journal of physiology. Endocrinology & metabolism. 2002; 283: E711 (#102013) |
| 63. | Timoney, J P; Malkin, M G; Leone, D M; Groeger, J S; Heaney, M L; Keefe, D L; Klang, M; Lucarelli, C D; Muller, R J; Eng, S L; Connor, M; Small, T N; Brown, A E; Saltz, L B. "Safe and cost effective use of alteplase for the clearance of occluded central venous access devices". Journal of clinical oncology. 2002; 20: 1918 (#102016) |
| 64. | Trimarchi, James R; Liu, Lin; Smith, Peter J S; Keefe, David L. "Apoptosis recruits two-pore domain potassium channels used for homeostatic volume regulation". American journal of physiology. Cell physiology. 2002; 282: C588 (#102018) |
| 65. | Wang, Wei Hua; Keefe, David L. "Prediction of chromosome misalignment among in vitro matured human oocytes by spindle imaging with the PolScope". Fertility & sterility. 2002; 78: 1077 (#102009) |
| 66. | Wang, Wei-Hua; Keefe, David L. "Spindle observation in living mammalian oocytes with the polarization microscope and its practical use". Cloning & stem cells. 2002; 4: 269 (#102010) |
| 67. | Wang, Wei-Hua; Meng, Li; Hackett, Richard J; Oldenbourg, Rudolf; Keefe, David L. "Rigorous thermal control during intracytoplasmic sperm injection stabilizes the meiotic spindle and improves fertilization and pregnancy rates". Fertility & sterility. 2002; 77: 1274 (#102014) |
| 68. | Bogolioubov, A; Keefe, D L; Groeger, J S. "Circulatory shock". Critical care clinics. 2001; 17: 697 (#102026) |
| 69. | Calzone, W L; Silva, C; Keefe, D L; Stachenfeld, N S. "Progesterone does not alter osmotic regulation of AVP". American journal of physiology. Regulatory, integrative, & comparative physiology. 2001; 281: R2011 (#102021) |
| 70. | Keefe, D L. "Anthracycline-induced cardiomyopathy". Seminars in oncology. 2001; 28: 2 (#102025) |
| 71. | Liu, L; Hammar, K; Smith, P J; Inoue, S; Keefe, D L. "Mitochondrial modulation of calcium signaling at the initiation of development". Cell calcium. 2001; 30: 423 (#102020) |
| 72. | Stachenfeld, N S; Keefe, D L; Palter, S F. "Estrogen and progesterone effects on transcapillary fluid dynamics". American journal of physiology. Regulatory, integrative, & comparative physiology. 2001; 281: R1319 (#102024) |
| 73. | Stachenfeld, N S; Splenser, A E; Calzone, W L; Taylor, M P; Keefe, D L. "Sex differences in osmotic regulation of AVP and renal sodium handling". Journal of applied physiology (Bethesda). 2001; 91: 1893 (#102023) |
| 74. | Wang, W H; Meng, L; Hackett, R J; Keefe, D L. "Developmental ability of human oocytes with or without birefringent spindles imaged by Polscope before insemination". Human reproduction. 2001; 16: 1464 (#102027) |
| 75. | Wang, W H; Meng, L; Hackett, R J; Odenbourg, R; Keefe, D L. "Limited recovery of meiotic spindles in living human oocytes after cooling-rewarming observed using polarized light microscopy". Human reproduction. 2001; 16: 2374 (#102022) |
| 76. | Wang, W H; Meng, L; Hackett, R J; Odenbourg, R; Keefe, D L. "The spindle observation and its relationship with fertilization after intracytoplasmic sperm injection in living human oocytes". Fertility & sterility. 2001; 75: 348 (#102029) |
| 77. | Colburn, W A; Keefe, D L. "Bioavailability and bioequivalence: average, population and/or individual". Journal of clinical pharmacology. 2000; 40: 559 (#102031) |
| 78. | Keefe, D L. "Cardiovascular emergencies in the cancer patient". Seminars in oncology. 2000; 27: 244 (#102032) |
| 79. | Keefe, D L. "Clinical pharmacology of telmisartan:". Journal of clinical pharmacology. 2000; 40: 1311 (#102028) |
| 80. | Liu, L; Keefe, D L. "Cytoplasm mediates both development and oxidation-induced apoptotic cell death in mouse zygotes". Biology of reproduction. 2000; 62: 1828 (#102036) |
| 81. | Liu, L; Oldenbourg, R; Trimarchi, J R; Keefe, D L. "A reliable, noninvasive technique for spindle imaging and enucleation of mammalian oocytes". Nature biotechnology. 2000; 18: 223 (#102039) |
| 82. | Liu, L; Trimarchi, J R; Keefe, D L. "Involvement of mitochondria in oxidative stress-induced cell death in mouse zygotes". Biology of reproduction. 2000; 62: 1745 (#102037) |
| 83. | Liu, L; Trimarchi, J R; Oldenbourg, R; Keefe, D L. "Increased birefringence in the meiotic spindle provides a new marker for the onset of activation in living oocytes". Biology of reproduction. 2000; 63: 251 (#102033) |
| 84. | Safdar, A; Childs, B H; Keefe, D; Sepkowitz, K A. "Acute bacterial endocarditis during granulocytopenia in an allogenic marrow transplant recipient". American journal of medicine. 2000; 109: 514 (#174323) |
| 85. | Stachenfeld, N S; Silva, C; Keefe, D L. "Estrogen modifies the temperature effects of progesterone". Journal of applied physiology (Bethesda). 2000; 88: 1643 (#102038) |
| 86. | Trimarchi, J R; Liu, L; Porterfield, D M; Smith, P J; Keefe, D L. "A non-invasive method for measuring preimplantation embryo physiology". Zygote. 2000; 8: 15 (#102034) |
| 87. | Trimarchi, J R; Liu, L; Porterfield, D M; Smith, P J; Keefe, D L. "Oxidative phosphorylation-dependent and -independent oxygen consumption by individual preimplantation mouse embryos". Biology of reproduction. 2000; 62: 1866 (#102035) |
| 88. | Trimarchi, J R; Liu, L; Smith, P J; Keefe, D L. "Noninvasive measurement of potassium efflux as an early indicator of cell death in mouse embryos". Biology of reproduction. 2000; 63: 851 (#102030) |
| 89. | Keefe, D L; Watson, R; Naftolin, F. "Hormone replacement therapy may alleviate sleep apnea in menopausal women: a pilot study". Menopause. 1999; 6: 196 (#102041) |
| 90. | Liu, L; Trimarchi, J R; Keefe, D L. "Thiol oxidation-induced embryonic cell death in mice is prevented by the antioxidant dithiothreitol". Biology of reproduction. 1999; 61: 1162 (#102040) |
| 91. | Pepperell, J R; Kommineni, K; Buradagunta, S; Smith, P J; Keefe, D L. "Transmembrane regulation of intracellular calcium by a plasma membrane sodium/calcium exchanger in mouse ova". Biology of reproduction. 1999; 60: 1137 (#102044) |
| 92. | Rinaudo, P; Niven-Fairchild, T; Buradagunta, S; Massobrio, M; Revelli, A; Keefe, D L. "Microinjection of mitochondria into zygotes creates a model for studying the inheritance of mitochondrial DNA during preimplantation development". Fertility & sterility. 1999; 71: 912 (#102043) |
| 93. | Silva, C P; Kommineni, K; Oldenbourg, R; Keefe, D L. "The first polar body does not predict accurately the location of the metaphase II meiotic spindle in mammalian oocytes". Fertility & sterility. 1999; 71: 719 (#102045) |
| 94. | Stachenfeld, N S; DiPietro, L; Kokoszka, C A; Silva, C; Keefe, D L; Nadel, E R. "Physiological variability of fluid-regulation hormones in young women". Journal of applied physiology (Bethesda). 1999; 86: 1092 (#102046) |
| 95. | Stachenfeld, N S; Silva, C; Keefe, D L; Kokoszka, C A; Nadel, E R. "Effects of oral contraceptives on body fluid regulation". Journal of applied physiology (Bethesda). 1999; 87: 1016 (#102042) |
| 96. | Greenfeld, D A; Greenfeld, D G; Mazure, C M; Keefe, D L; Olive, D L. "Do attitudes toward disclosure in donor oocyte recipients predict the use of anonymous versus directed donation?". Fertility & sterility. 1998; 70: 1009 (#102047) |
| 97. | Hudis C; Riccio L; Seidman A; Baselga J; Currie V; Fennelly D; Gilewski T; Lebwohl D; Moynahan M; Raptis G; Surbone A; Sklarin N; Yao TJ; Keefe D; Norton L. "Lack of increased cardiac toxicity with sequential doxorubicin and paclitaxel". Cancer investigation. 1998; 16: 67 (#38037) |
| 98. | Keefe, D L. "Reproductive aging is an evolutionarily programmed strategy that no longer provides adaptive value". Fertility & sterility. 1998; 70: 204 (#102049) |
| 99. | Porterfield, D M; Trimarchi, J R; Keefe, D L; Smith, P J. "Characterization of oxygen and calcium fluxes from early mouse embryos and oocytes". Biological bulletin. 1998; 195: 208 (#102048) |
| 100. | Keefe, D L. "Aging and infertility in women". Medicine & health, Rhode Island. 1997; 80: 403 (#102050) |
| 101. | Rinaudo, P; Pepperell, J R; Buradgunta, S; Massobrio, M; Keefe, D L. "Dissociation between intracellular calcium elevation and development of human oocytes treated with calcium ionophore". Fertility & sterility. 1997; 68: 1086 (#102051) |
| 102. | Colburn, W A; Keefe, D L. "Who is responsible for clinical pharmacology?". Journal of clinical pharmacology. 1996; 36: 383 (#102054) |
| 103. | Dickey, K W; Zreik, T G; Hsia, H C; Eschelman, D J; Keefe, D L; Olive, D L; Pollak, J S; Rosenblatt, M; Glickman, M G. "Transvaginal uterine cervical dilation with fluoroscopic guidance: preliminary results in patients with infertility". Radiology. 1996; 200: 497 (#102053) |
| 104. | Keefe, D L; Sarrel, P. "Dependency on progesterone in woman with self-diagnosed premenstrual syndrome". Lancet. 1996; 347: 1182 (#102055) |
| 105. | Zreik TG; Dickey KW; Keefe DL; Glickman MG; Olive DL. "Fluoroscopically Guided Cervical Dilatation in Patients with Infertility". Journal of the American Association of Gynecologic Laparoscopists. 1996; 3: S56 (#102052) |
| 106. | Greenfeld, D A; Mazure, C M; Olive, D L; Keefe, D L. "Similarities and differences between anonymous and directed candidates for oocyte donation". Journal of assisted reproduction & genetics. 1995; 12: 118 (#102057) |
| 107. | Keefe, D L; Niven-Fairchild, T; Powell, S; Buradagunta, S. "Mitochondrial deoxyribonucleic acid deletions in oocytes and reproductive aging in women". Fertility & sterility. 1995; 64: 577 (#102056) |
| 108. | Nathan, J D; Keefe, D L; Weinstein, M A; Chen, Z; Naftolin, F. "Estrogen mustard induces cell cycle arrest of human epithelial ovarian cancer cell lines". Journal of the Society for Gynecologic Investigation. 1994; 1: 97 (#102058) |
| 109. | SEIFER, DB; ROAPENA, L; KEEFE, DL; ZHANG, HP; GOODMAN, S; JONES, EE; NAFTOLIN, F. "INCREASING HYPOTHALAMIC ARCUATE NUCLEUS GLIAL PEROXIDASE-ACTIVITY IN AGING FEMALE RATS IS REDUCED BY AN ANTIESTROGEN AND A GONADOTROPIN-RELEASING-HORMONE AGONIST". Menopause. 1994; 1: 83 (#103013) |
| 110. | Keefe, DL; Moore, TC; Stein, M; Naftolin, F. "Neuron-glial Interactions In The Estrogen-sensitive Zone Of Reaction Of The Rat Hypothalamus". 1993; 33 (#5188) |
| 111. | Piepmeier, J M; Keefe, D L; Weinstein, M A; Yoshida, D; Zielinski, J; Lin, T T; Chen, Z; Naftolin, F. "Estramustine and estrone analogs rapidly and reversibly inhibit deoxyribonucleic acid synthesis and alter morphology in cultured human glioblastoma cells". Neurosurgery. 1993; 32: 422 (#102059) |
| 112. | Pincus, S M; Keefe, D L. "Quantification of hormone pulsatility via an approximate entropy algorithm". American journal of physiology. 1992; 262: E741 (#102061) |
| 113. | Keefe DL; Michelson DS; Naftolin F. "Estrogen-effects On The Organization Of The Rat Brain Astrocytes Within The Hypothalamic Arcuate Nucleus Contain Estrogen-sensitive Peroxidase Activity And May Mediate Synaptic Plasticity In The Rat". 1991; 265 (#5820) |
| 114. | Keefe, D L; Michelson, D S; Lee, S H; Naftolin, F. "Astrocytes within the hypothalamic arcuate nucleus contain estrogen-sensitive peroxidase, bind fluorescein-conjugated estradiol, and may mediate synaptic plasticity in the rat". American journal of obstetrics & gynecology. 1991; 164: 959 (#102063) |
| 115. | Keefe, D L; Earnest, D J; Nelson, D; Takahashi, J S; Turek, F W. "A cholinergic antagonist, mecamylamine, blocks the phase-shifting effects of light on the circadian rhythm of locomotor activity in the golden hamster". Brain research. 1987; 403: 308 (#102064) |
| 116. | Keefe, D L; Turek, F W. "Circadian time keeping processes in mammalian reproduction". Oxford reviews of reproductive biology. 1985; 7: 346 (#102066) |
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