Recent Publications by Dr. David Keefe

Publications

Publications

1. Huang, Junjiu; Wang, Fang; Okuka, Maja; Liu, Na; Ji, Guangzhen; Ye, Xiaoying; Zuo, Bingfeng; Li, Minshu; Liang, Ping; Ge, William W; Tsibris, John Cm; Keefe, David L; Liu, Lin. "Association of telomere length with authentic pluripotency of ES/iPS cells". Cell research. 2011; 21: 779 (#J0218505)
2. Liu, Zhong; Hu, Zhe; Pan, Xinghua; Li, Minshu; Togun, Taiwo A; Tuck, David; Pelizzola, Mattia; Huang, Junjiu; Ye, Xiaoying; Yin, Yu; Liu, Mengyuan; Li, Chao; Chen, Zhisheng; Wang, Fang; Zhou, Lingjun; Chen, Lingyi; Keefe, David L; Liu, Lin. "Germline competency of parthenogenetic embryonic stem cells from immature oocytes of adult mouse ovary". Human molecular genetics. 2011; 20: 1339 (#J0218506)
3. Agarwal, Suneet; Loh, Yuin-Han; McLoughlin, Erin M; Huang, Junjiu; Park, In-Hyun; Miller, Justine D; Huo, Hongguang; Okuka, Maja; Dos Reis, Rosana Maria; Loewer, Sabine; Ng, Huck-Hui; Keefe, David L; Goldman, Frederick D; Klingelhutz, Aloysius J; Liu, Lin; Daley, George Q. "Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients". Nature. 2010; 464: 292 (#J0218510)
4. Huang, Junjiu; Okuka, Maja; Wang, Fang; Zuo, Bingfeng; Liang, Ping; Kalmbach, Keri; Liu, Lin; Keefe, David L. "Generation of pluripotent stem cells from eggs of aging mice". Aging Cell. 2010; 9: 113 (#J0218509)
5. Huang, Junjiu; Okuka, Maja; McLean, Mark; Keefe, David L; Liu, Lin. "Telomere susceptibility to cigarette smoke-induced oxidative damage and chromosomal instability of mouse embryos in vitro". Free radical biology & medicine. 2010; 48: 1663 (#J0218508)
6. Liu, Na; Enkemann, Steven A; Liang, Ping; Hersmus, Remko; Zanazzi, Claudia; Huang, Junjiu; Wu, Chao; Chen, Zhisheng; Looijenga, Leendert H J; Keefe, David L; Liu, Lin. "Genome-wide gene expression profiling reveals aberrant MAPK and Wnt signaling pathways associated with early parthenogenesis". Journal of molecular cell biology. 2010; 2: 333 (#J0218507)
7. Palatini, P; Jung, W; Shlyakhto, E; Botha, J; Bush, C; Keefe, D L. "Maintenance of blood-pressure-lowering effect following a missed dose of aliskiren, irbesartan or ramipril: results of a randomized, double-blind study". Journal of human hypertension. 2010; 24: 93 (#J0175867)
8. Quinn, Gwendolyn P; Vadaparampil, Susan T; Jacobsen, Paul B; Knapp, Caprice; Keefe, David L; Bell, Geri E. "Frozen hope: fertility preservation for women with cancer". Journal of Midwifery & Women's Health. 2010; 55: 175 (#J0231543)
9. Chen, Zhisheng; Liu, Zhong; Huang, Junjiu; Amano, Tomokazu; Li, Chao; Cao, Shanbo; Wu, Chao; Liu, Bodu; Zhou, Lingjun; Carter, Mark G; Keefe, David L; Yang, Xiangzhong; Liu, Lin. "Birth of Parthenote Mice Directly from Parthenogenetic Embryonic Stem Cells". Stem cells. 2009; 27: 2136 (#J0175866)
10. Huang, Junjiu; Okuka, Maja; McLean, Mark; Keefe, David L; Liu, Lin. "Effects of cigarette smoke on fertilization and embryo development in vivo". Fertility & sterility. 2009; 92: 1456 (#J0175872)
11. Keefe, David L; Liu, Lin. "Telomeres and reproductive aging". Reproduction, fertility & development. 2009; 21: 10 (#J0175871)
12. Li, Chao; Chen, Zhisheng; Liu, Zhong; Huang, Junjiu; Zhang, Wei; Zhou, Lingjun; Keefe, David L; Liu, Lin. "Correlation of expression and methylation of imprinted genes with pluripotency of parthenogenetic embryonic stem cells". Human molecular genetics. 2009; 18: 2177 (#J0175869)
13. Quinn, Gwendolyn P; Vadaparampil, Susan T; Lee, Ji-Hyun; Jacobsen, Paul B; Bepler, Gerold; Lancaster, Johnathan; Keefe, David L; Albrecht, Terrance L. "Physician referral for fertility preservation in oncology patients: a national study of practice behaviors". Journal of clinical oncology. 2009; 27: 5952 (#J0231544)
14. Silberstein, Tali; Saphier, Oshra; Paz-Tal, Ofra; Gonzalez, Liliana; Keefe, David L; Trimarchi, James R. "Trace element concentrations in follicular fluid of small follicles differ from those in blood serum, and may represent long-term exposure". Fertility & sterility. 2009; 91: 1771 (#J0175875)
15. Huang, Junjiu; Deng, Kai; Wu, Haojia; Liu, Zhong; Chen, Zhisheng; Cao, Shanbo; Zhou, Lingjun; Ye, Xiaoying; Keefe, David L; Liu, Lin. "Efficient production of mice from embryonic stem cells injected into four- or eight-cell embryos by piezo micromanipulation". Stem cells. 2008; 26: 1883 (#J0175874)
16. Liu, Lin; Keefe, David L. "Defective cohesin is associated with age-dependent misaligned chromosomes in oocytes". Reproductive biomedicine online. 2008; 16: 103 (#J0175877)
17. Keefe, D L; Liu, L; Marquard, K. "Telomeres and aging-related meiotic dysfunction in women". Cellular & molecular life sciences: CMLS. 2007; 64: 139 (#J0175886)
18. Keefe, D L. "Telomeres and meiosis in health and disease". Cellular & molecular life sciences: CMLS. 2007; 64: 115 (#J0175885)
19. Liu, Yifei; Wu, Chao; Lyu, Qifeng; Yang, Dongzi; Albertini, David F; Keefe, David L; Liu, Lin. "Germline stem cells and neo-oogenesis in the adult human ovary". Developmental biology (Orlando). 2007; 306: 112 (#J0175881)
20. Liu, Lin; Keefe, David L. "Nuclear transfer methods to study aging". Methods in molecular biology. 2007; 371: 191 (#J0175880)
21. Liu, Lin; Bailey, Susan M; Okuka, Maja; Munoz, Purificacion; Li, Chao; Zhou, Lingjun; Wu, Chao; Czerwiec, Eva; Sandler, Laurel; Seyfang, Andreas; Blasco, Maria A; Keefe, David L. "Telomere lengthening early in development". Nature cell biology. 2007; 9: 1436 (#J0175878)
22. Dai, Yunping; Wang, Lili; Wang, Haiping; Liu, Ying; Li, Ning; Lyu, Qifeng; Keefe, David L; Albertini, David F; Liu, Lin. "Fate of centrosomes following somatic cell nuclear transfer (SCNT) in bovine oocytes". Reproduction. 2006; 131: 1051 (#J0175889)
23. Keefe, David L; Marquard, Kerri; Liu, Lin. "The telomere theory of reproductive senescence in women". Current opinion in obstetrics & gynecology. 2006; 18: 280 (#J0175888)
24. Navarro, Paula A A S; Liu, Lin; Ferriani, Rui A; Keefe, David L. "Arsenite induces aberrations in meiosis that can be prevented by coadministration of N-acetylcysteine in mice". Fertility & sterility. 2006; 85 Suppl 1: 1187 (#J0175890)
25. Silberstein, Tali; Saphier, Oshra; Paz-Tal, Ofra; Trimarchi, James R; Gonzalez, Liliana; Keefe, David L. "Lead concentrates in ovarian follicle compromises pregnancy". Journal of trace elements in medicine & biology. 2006; 20: 205 (#J0175887)
26. Silberstein, T; MacLaughlin, D T; Shai, I; Trimarchi, J R; Lambert-Messerlian, G; Seifer, D B; Keefe, D L; Blazar, A S. "Mullerian inhibiting substance levels at the time of HCG administration in IVF cycles predict both ovarian reserve and embryo morphology". Human reproduction. 2006; 21: 159 (#J0175894)
27. Trimarchi, James Robert; Keefe, David L. "Assessing the quality of oocytes derived from in vitro maturation: are we looking under the lamppost? [comment]". Fertility & sterility. 2006; 85: 839 (#J0175891)
28. Keefe, David L; Parry, John P. "New approaches to assisted reproductive technologies". Seminars in reproductive medicine. 2005; 23: 301 (#J0175892)
29. Keefe, David L; Franco, Sonia; Liu, Lin; Trimarchi, James; Cao, Benning; Weitzen, Sherry; Agarwal, Shoba; Blasco, Maria A. "Telomere length predicts embryo fragmentation after in vitro fertilization in women--toward a telomere theory of reproductive aging in women". American journal of obstetrics & gynecology. 2005; 192: 1256 (#J0175895)
30. Navarro, Paula A A S; Liu, Lin; Trimarchi, James R; Ferriani, Rui A; Keefe, David L. "Noninvasive imaging of spindle dynamics during mammalian oocyte activation". Fertility & sterility. 2005; 83 Suppl 1: 1197 (#J0175896)
31. Silberstein, Tali; Trimarchi, James R; Gonzalez, Liliana; Keefe, David L; Blazar, Andrew S. "Pregnancy outcome in in vitro fertilization decreases to a plateau with repeated cycles". Fertility & sterility. 2005; 84: 1043 (#J0175893)
32. Stachenfeld, Nina S; Keefe, David L; Taylor, Hugh S. "Responses to a saline load in gonadotropin-releasing hormone antagonist-pretreated premenopausal women receiving progesterone or estradiol-progesterone therapy". Journal of clinical endocrinology & metabolism. 2005; 90: 386 (#J0175899)
33. Abizaid, Alfonso; Horvath, Balazs; Keefe, David L; Leranth, Csaba; Horvath, Tamas L. "Direct visual and circadian pathways target neuroendocrine cells in primates". European journal of neuroscience. 2004; 20: 2767 (#J0175897)
34. Blazar, Andrew S; Hogan, Joseph W; Frankfurter, David; Hackett, Richard; Keefe, David L. "Serum estradiol positively predicts outcomes in patients undergoing in vitro fertilization [letter]". Fertility & sterility. 2004; 81: 1707 (#J0175902)
35. Frankfurter, David; Trimarchi, James B; Silva, Celso P; Keefe, David L. "Middle to lower uterine segment embryo transfer improves implantation and pregnancy rates compared with fundal embryo transfer". Fertility & sterility. 2004; 81: 1273 (#J0175904)
36. Frankfurter, David; Trimarchi, James; Hackett, Rick; Meng, Li; Keefe, David. "Monozygotic pregnancies from transfers of zona-free blastocysts [letter]". Fertility & sterility. 2004; 82: 483 (#J0231747)
37. Liu, Lin; Czerwiec, Eva; Keefe, David L. "Effect of ploidy and parental genome composition on expression of Oct-4 protein in mouse embryos". Gene expression patterns. 2004; 4: 433 (#J0175903)
38. Liu, Lin; Franco, Sonia; Spyropoulos, Barbara; Moens, Peter B; Blasco, Maria A; Keefe, David L. "Irregular telomeres impair meiotic synapsis and recombination in mice". Proceedings of the National Academy of Sciences of the United States of America. 2004; 101: 6496 (#J0175905)
39. Liu, Lin; Keefe, David L. "Nuclear origin of aging-associated meiotic defects in senescence-accelerated mice". Biology of reproduction. 2004; 71: 1724 (#J0175900)
40. Liu, Lin; DiGirolamo, Carla M; Navarro, Paula A A S; Blasco, Maria A; Keefe, David L. "Telomerase deficiency impairs differentiation of mesenchymal stem cells". Experimental cell research. 2004; 294: 1 (#J0175907)
41. Navarro, Paula A A S; Liu, Lin; Keefe, David L. "In vivo effects of arsenite on meiosis, preimplantation development, and apoptosis in the mouse". Biology of reproduction. 2004; 70: 980 (#J0175908)
42. Pelletier, Cory; Keefe, David L; Trimarchi, James R. "Noninvasive polarized light microscopy quantitatively distinguishes the multilaminar structure of the zona pellucida of living human eggs and embryos". Fertility & sterility. 2004; 81 Suppl 1: 850 (#J0175906)
43. Silberstein, Tali; Weitzen, Sherry; Frankfurter, David; Trimarchi, James R; Keefe, David L; Plosker, Shayne M. "Cannulation of a resistant internal os with the malleable outer sheath of a coaxial soft embryo transfer catheter does not affect in vitro fertilization-embryo transfer outcome". Fertility & sterility. 2004; 82: 1402 (#J0175898)
44. Sun, Xiao-Fang; Wang, Wei-Hua; Keefe, David L. "Overheating is detrimental to meiotic spindles within in vitro matured human oocytes". Zygote. 2004; 12: 65 (#J0175901)
45. Dubowy, Rebecca L; Feinberg, Ronald F; Keefe, David L; Doncel, Gustavo F; Williams, Shaun C; McSweet, Juliette C; Kliman, Harvey J. "Improved endometrial assessment using cyclin E and p27". Fertility & sterility. 2003; 80: 146 (#J0175912)
46. Frankfurter, David; Silva, Celso P; Mota, Francisco; Trimarchi, James B; Keefe, David L. "The transfer point is a novel measure of embryo placement". Fertility & sterility. 2003; 79: 1416 (#J0175913)
47. Keefe, David; Liu, Lin; Wang, Wei; Silva, Celso. "Imaging meiotic spindles by polarization light microscopy: principles and applications to IVF". Reproductive biomedicine online. 2003; 7: 24 (#J0218511)
48. Liu, Lin; Trimarchi, James R; Navarro, Paula; Blasco, Maria A; Keefe, David L. "Oxidative stress contributes to arsenic-induced telomere attrition, chromosome instability, and apoptosis". Journal of biological chemistry. 2003; 278: 31998 (#J0175914)
49. Pepperell, John R; Porterfield, D Marshall; Keefe, David L; Behrman, Harold R; Smith, Peter J S. "Control of ascorbic acid efflux in rat luteal cells: role of intracellular calcium and oxygen radicals". American journal of physiology. Cell physiology. 2003; 285: C642 (#J0175915)
50. Stachenfeld, Nina S; Taylor, Hugh S; Leone, Cheryl A; Keefe, David L. "Oestrogen effects on urine concentrating response in young women". Journal of physiology. 2003; 552: 869 (#J0175910)
51. Keefe, David L. "Sex hormones and neural mechanisms". Archives of sexual behaviour. 2002; 31: 401 (#J0175919)
52. Liu, Lin; Keefe, David L. "Ageing-associated aberration in meiosis of oocytes from senescence-accelerated mice". Human reproduction. 2002; 17: 2678 (#J0175918)
53. Liu, Lin; Trimarchi, James R; Smith, Peter J S; Keefe, David L. "Checkpoint for DNA integrity at the first mitosis after oocyte activation". Molecular reproduction & development. 2002; 62: 277 (#J0175923)
54. Liu, Lin; Blasco, Maria; Trimarchi, James; Keefe, David. "An essential role for functional telomeres in mouse germ cells during fertilization and early development". Developmental biology (Orlando). 2002; 249: 74 (#J0218512)
55. Liu, Lin; Trimarchi, James R; Keefe, David L. "Haploidy but not parthenogenetic activation leads to increased incidence of apoptosis in mouse embryos". Biology of reproduction. 2002; 66: 204 (#J0175928)
56. Liu, Lin; Trimarchi, James R; Smith, Peter J S; Keefe, David L. "Mitochondrial dysfunction leads to telomere attrition and genomic instability". Aging Cell. 2002; 1: 40 (#J0175911)
57. Liu, Lin; Blasco, Maria A; Keefe, David L. "Requirement of functional telomeres for metaphase chromosome alignments and integrity of meiotic spindles". EMBO reports. 2002; 3: 230 (#J0175925)
58. Stachenfeld, Nina S; Keefe, David L. "Estrogen effects on osmotic regulation of AVP and fluid balance". American journal of physiology. Endocrinology & metabolism. 2002; 283: E711 (#J0175921)
59. Timoney, J P; Malkin, M G; Leone, D M; Groeger, J S; Heaney, M L; Keefe, D L; Klang, M; Lucarelli, C D; Muller, R J; Eng, S L; Connor, M; Small, T N; Brown, A E; Saltz, L B. "Safe and cost effective use of alteplase for the clearance of occluded central venous access devices". Journal of clinical oncology. 2002; 20: 1918 (#J0175924)
60. Trimarchi, James R; Liu, Lin; Smith, Peter J S; Keefe, David L. "Apoptosis recruits two-pore domain potassium channels used for homeostatic volume regulation". American journal of physiology. Cell physiology. 2002; 282: C588 (#J0175927)
61. Wang, Wei Hua; Keefe, David L. "Prediction of chromosome misalignment among in vitro matured human oocytes by spindle imaging with the PolScope". Fertility & sterility. 2002; 78: 1077 (#J0175916)
62. Wang, Wei-Hua; Meng, Li; Hackett, Richard J; Oldenbourg, Rudolf; Keefe, David L. "Rigorous thermal control during intracytoplasmic sperm injection stabilizes the meiotic spindle and improves fertilization and pregnancy rates". Fertility & sterility. 2002; 77: 1274 (#J0175922)
63. Wang, Wei-Hua; Keefe, David L. "Spindle observation in living mammalian oocytes with the polarization microscope and its practical use". Cloning & stem cells. 2002; 4: 269 (#J0175917)
64. Bogolioubov, A; Keefe, D L; Groeger, J S. "Circulatory shock". Critical care clinics. 2001; 17: 697 (#J0175935)
65. Calzone, W L; Silva, C; Keefe, D L; Stachenfeld, N S. "Progesterone does not alter osmotic regulation of AVP". American journal of physiology. Regulatory, integrative, & comparative physiology. 2001; 281: R2011 (#J0175930)
66. Keefe, D L. "Anthracycline-induced cardiomyopathy". Seminars in oncology. 2001; 28: 2 (#J0175934)
67. Liu, L; Hammar, K; Smith, P J; Inoue, S; Keefe, D L. "Mitochondrial modulation of calcium signaling at the initiation of development". Cell calcium. 2001; 30: 423 (#J0175929)
68. Stachenfeld, N S; Keefe, D L; Palter, S F. "Estrogen and progesterone effects on transcapillary fluid dynamics". American journal of physiology. Regulatory, integrative, & comparative physiology. 2001; 281: R1319 (#J0175933)
69. Stachenfeld, N S; Splenser, A E; Calzone, W L; Taylor, M P; Keefe, D L. "Sex differences in osmotic regulation of AVP and renal sodium handling". Journal of applied physiology (Bethesda). 2001; 91: 1893 (#J0175932)
70. Wang, W H; Meng, L; Hackett, R J; Keefe, D L. "Developmental ability of human oocytes with or without birefringent spindles imaged by Polscope before insemination". Human reproduction. 2001; 16: 1464 (#J0175936)
71. Wang, W H; Meng, L; Hackett, R J; Odenbourg, R; Keefe, D L. "Limited recovery of meiotic spindles in living human oocytes after cooling-rewarming observed using polarized light microscopy". Human reproduction. 2001; 16: 2374 (#J0175931)
72. Wang, W H; Meng, L; Hackett, R J; Odenbourg, R; Keefe, D L. "The spindle observation and its relationship with fertilization after intracytoplasmic sperm injection in living human oocytes". Fertility & sterility. 2001; 75: 348 (#J0175938)
73. Colburn, W A; Keefe, D L. "Bioavailability and bioequivalence: average, population and/or individual [editorial]". Journal of clinical pharmacology. 2000; 40: 559 (#J0175940)
74. Keefe, D L. "Cardiovascular emergencies in the cancer patient". Seminars in oncology. 2000; 27: 244 (#J0175941)
75. Keefe, D L. "Clinical pharmacology of telmisartan: [editorial]". Journal of clinical pharmacology. 2000; 40: 1311 (#J0175937)
76. Liu, L; Keefe, D L. "Cytoplasm mediates both development and oxidation-induced apoptotic cell death in mouse zygotes". Biology of reproduction. 2000; 62: 1828 (#J0175945)
77. Liu, L; Trimarchi, J R; Oldenbourg, R; Keefe, D L. "Increased birefringence in the meiotic spindle provides a new marker for the onset of activation in living oocytes". Biology of reproduction. 2000; 63: 251 (#J0175942)
78. Liu, L; Trimarchi, J R; Keefe, D L. "Involvement of mitochondria in oxidative stress-induced cell death in mouse zygotes". Biology of reproduction. 2000; 62: 1745 (#J0175946)
79. Liu, L; Oldenbourg, R; Trimarchi, J R; Keefe, D L. "A reliable, noninvasive technique for spindle imaging and enucleation of mammalian oocytes". Nature biotechnology. 2000; 18: 223 (#J0175948)
80. Stachenfeld, N S; Silva, C; Keefe, D L. "Estrogen modifies the temperature effects of progesterone". Journal of applied physiology (Bethesda). 2000; 88: 1643 (#J0175947)
81. Trimarchi, J R; Liu, L; Smith, P J; Keefe, D L. "Noninvasive measurement of potassium efflux as an early indicator of cell death in mouse embryos". Biology of reproduction. 2000; 63: 851 (#J0175939)
82. Trimarchi, J R; Liu, L; Porterfield, D M; Smith, P J; Keefe, D L. "A non-invasive method for measuring preimplantation embryo physiology". Zygote. 2000; 8: 15 (#J0175943)
83. Trimarchi, J R; Liu, L; Porterfield, D M; Smith, P J; Keefe, D L. "Oxidative phosphorylation-dependent and -independent oxygen consumption by individual preimplantation mouse embryos". Biology of reproduction. 2000; 62: 1866 (#J0175944)
84. Keefe, D L; Watson, R; Naftolin, F. "Hormone replacement therapy may alleviate sleep apnea in menopausal women: a pilot study". Menopause. 1999; 6: 196 (#J0175950)
85. Liu, L; Trimarchi, J R; Keefe, D L. "Thiol oxidation-induced embryonic cell death in mice is prevented by the antioxidant dithiothreitol". Biology of reproduction. 1999; 61: 1162 (#J0175949)
86. Pepperell, J R; Kommineni, K; Buradagunta, S; Smith, P J; Keefe, D L. "Transmembrane regulation of intracellular calcium by a plasma membrane sodium/calcium exchanger in mouse ova". Biology of reproduction. 1999; 60: 1137 (#J0175953)
87. Rinaudo, P; Niven-Fairchild, T; Buradagunta, S; Massobrio, M; Revelli, A; Keefe, D L. "Microinjection of mitochondria into zygotes creates a model for studying the inheritance of mitochondrial DNA during preimplantation development". Fertility & sterility. 1999; 71: 912 (#J0175952)
88. Silva, C P; Kommineni, K; Oldenbourg, R; Keefe, D L. "The first polar body does not predict accurately the location of the metaphase II meiotic spindle in mammalian oocytes". Fertility & sterility. 1999; 71: 719 (#J0175954)
89. Stachenfeld, N S; Silva, C; Keefe, D L; Kokoszka, C A; Nadel, E R. "Effects of oral contraceptives on body fluid regulation". Journal of applied physiology (Bethesda). 1999; 87: 1016 (#J0175951)
90. Stachenfeld, N S; DiPietro, L; Kokoszka, C A; Silva, C; Keefe, D L; Nadel, E R. "Physiological variability of fluid-regulation hormones in young women". Journal of applied physiology (Bethesda). 1999; 86: 1092 (#J0175955)
91. Greenfeld, D A; Greenfeld, D G; Mazure, C M; Keefe, D L; Olive, D L. "Do attitudes toward disclosure in donor oocyte recipients predict the use of anonymous versus directed donation?". Fertility & sterility. 1998; 70: 1009 (#J0175956)
92. Hudis C; Riccio L; Seidman A; Baselga J; Currie V; Fennelly D; Gilewski T; Lebwohl D; Moynahan M; Raptis G; Surbone A; Sklarin N; Yao TJ; Keefe D; Norton L. "Lack of increased cardiac toxicity with sequential doxorubicin and paclitaxel". Cancer investigation. 1998; 16: 67 (#J0051770)
93. Keefe, D L. "Reproductive aging is an evolutionarily programmed strategy that no longer provides adaptive value [editorial]". Fertility & sterility. 1998; 70: 204 (#J0175958)
94. Porterfield, D M; Trimarchi, J R; Keefe, D L; Smith, P J. "Characterization of oxygen and calcium fluxes from early mouse embryos and oocytes". Biological bulletin. 1998; 195: 208 (#J0175957)
95. Keefe, D L. "Aging and infertility in women". Medicine & health, Rhode Island. 1997; 80: 403 (#J0175959)
96. Rinaudo, P; Pepperell, J R; Buradgunta, S; Massobrio, M; Keefe, D L. "Dissociation between intracellular calcium elevation and development of human oocytes treated with calcium ionophore". Fertility & sterility. 1997; 68: 1086 (#J0175960)
97. Colburn, W A; Keefe, D L. "Who is responsible for clinical pharmacology? [editorial]". Journal of clinical pharmacology. 1996; 36: 383 (#J0175963)
98. Dickey, K W; Zreik, T G; Hsia, H C; Eschelman, D J; Keefe, D L; Olive, D L; Pollak, J S; Rosenblatt, M; Glickman, M G. "Transvaginal uterine cervical dilation with fluoroscopic guidance: preliminary results in patients with infertility". Radiology. 1996; 200: 497 (#J0175962)
99. Keefe, D L; Sarrel, P. "Dependency on progesterone in woman with self-diagnosed premenstrual syndrome [letter]". Lancet. 1996; 347: 1182 (#J0175964)
100. Zreik TG; Dickey KW; Keefe DL; Glickman MG; Olive DL. "Fluoroscopically Guided Cervical Dilatation in Patients with Infertility". Journal of the American Association of Gynecologic Laparoscopists. 1996; 3: S56 (#J0175961)
101. Greenfeld, D A; Mazure, C M; Olive, D L; Keefe, D L. "Similarities and differences between anonymous and directed candidates for oocyte donation". Journal of assisted reproduction & genetics. 1995; 12: 118 (#J0175966)
102. Keefe, D L; Niven-Fairchild, T; Powell, S; Buradagunta, S. "Mitochondrial deoxyribonucleic acid deletions in oocytes and reproductive aging in women". Fertility & sterility. 1995; 64: 577 (#J0175965)
103. Nathan, J D; Keefe, D L; Weinstein, M A; Chen, Z; Naftolin, F. "Estrogen mustard induces cell cycle arrest of human epithelial ovarian cancer cell lines". Journal of the Society for Gynecologic Investigation. 1994; 1: 97 (#J0175969)
104. SEIFER, DB; ROAPENA, L; KEEFE, DL; ZHANG, HP; GOODMAN, S; JONES, EE; NAFTOLIN, F. "INCREASING HYPOTHALAMIC ARCUATE NUCLEUS GLIAL PEROXIDASE-ACTIVITY IN AGING FEMALE RATS IS REDUCED BY AN ANTIESTROGEN AND A GONADOTROPIN-RELEASING-HORMONE AGONIST". Menopause. 1994; 1: 83 (#J0177466)
105. Keefe, DL; Moore, TC; Stein, M; Naftolin, F. "Neuron-glial Interactions In The Estrogen-sensitive Zone Of Reaction Of The Rat Hypothalamus" IN: In: Local systems in reproduction New York : Raven Press, 1993, , p.33-39. 1993; 33 (#C0003148)
106. Piepmeier, J M; Keefe, D L; Weinstein, M A; Yoshida, D; Zielinski, J; Lin, T T; Chen, Z; Naftolin, F. "Estramustine and estrone analogs rapidly and reversibly inhibit deoxyribonucleic acid synthesis and alter morphology in cultured human glioblastoma cells". Neurosurgery. 1993; 32: 422 (#J0175971)
107. Pincus, S M; Keefe, D L. "Quantification of hormone pulsatility via an approximate entropy algorithm". American journal of physiology. 1992; 262: E741 (#J0175973)
108. Keefe, D L; Michelson, D S; Lee, S H; Naftolin, F. "Astrocytes within the hypothalamic arcuate nucleus contain estrogen-sensitive peroxidase, bind fluorescein-conjugated estradiol, and may mediate synaptic plasticity in the rat". American journal of obstetrics & gynecology. 1991; 164: 959 (#J0175976)
109. Keefe DL; Michelson DS; Naftolin F. "Estrogen-effects On The Organization Of The Rat Brain Astrocytes Within The Hypothalamic Arcuate Nucleus Contain Estrogen-sensitive Peroxidase Activity And May Mediate Synaptic Plasticity In The Rat" IN: In: The new biology of steroid hormones New York : Raven Press, 1991, , p.265-274. 1991; 265 (#C0003819)
110. Keefe, D L; Earnest, D J; Nelson, D; Takahashi, J S; Turek, F W. "A cholinergic antagonist, mecamylamine, blocks the phase-shifting effects of light on the circadian rhythm of locomotor activity in the golden hamster". Brain research. 1987; 403: 308 (#J0175980)
111. Keefe, D L; Turek, F W. "Circadian time keeping processes in mammalian reproduction". Oxford reviews of reproductive biology. 1985; 7: 346 (#J0175992)

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